What is Actifit®
Orteq targeted knee injuries first with Actifit® because there is no option to regenerate a patient’s meniscus once the damaged section of the meniscus has been removed via a partial meniscectomy. Every year there are more than 1,500,000 meniscectomies and 630,000 total knee replacements performed in the US and Europe. Therefore, Actifit® has the potential to satisfy a major unmet clinical need.
We believe that this biodegradable scaffold can be adapted for use throughout the body and will help promote new tissue in-growth in a variety of areas of the body.
Actifit® helps facilitate the human body’s natural healing process by providing the material into which blood can flow and reach the injured area and with it the oxygen, nutrients and fibroblasts needed for new cellular in-growth.
A meniscus tear is normally repaired by the removal of the torn or damaged tissue via a partial meniscectomy. This can be effective in the short term but often it only gives temporary pain relief. In many cases the pain returns in time due to the loss of meniscal tissue and the cushioning function provided by a healthy meniscus. Over a longer period there is overwhelming evidence that degenerative changes occur, which, if left untreated, can lead to articular cartilage damage, the onset of osteoarthritis and eventually a total knee replacement.
Actifit® is a honeycomb scaffold that enables blood to flow through it and provide an anchor for new cellular in-growth as the body’s natural healing process takes place. Once the damaged section of the meniscus has been cut away and the meniscus resected to an area with good blood supply, the Actifit® implant is cut to size and stitched into place. Over time, the new cellular in-growth matures into new meniscus like tissue. This will help restore the cushioning function of the meniscus and delay the onset of osteoarthritis.