Regenerative tissue engineering strategies have been used in an attempt to provide a new generation
of meniscal implants, either for partial or total replacement. The goal is to
provide biomaterials (acellular or cell-seeded constructs) which provide the
biomechanical properties but also the biological features to replace the loss of
native tissue. Moreover, these approaches include possibilities for
patient-specific implants of correct size and shape, as well as advanced
strategies combining cells, bioactive agents, hydrogels or gene therapy.Herein,
the clinical evidence and tips concerning MAT, currently available meniscus
scaffolds and future perspectives are discussed.
