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2022 - Review

Meniscus Substitution

de Caro F, Grammens J, Van Genechten W, Verdonk R, Verdonk PC.
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2022 - Review

Current state of off the shelf scaffolds and implants for meniscal replacement

Ghisa C, Zaslav KR
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2022 - Clinical Study

Integration of polyurethane meniscus scaffold during ACL revision is not reliable at 5 years despite favourable clinical outcome

Pereira H, Cengiz IF, Silva‑Correia J, Oliveira JM., Vasconcelos JC, Gomes S, Ripoll PL, Karlsson J, Reis RL, Espregueira-Mendes J
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2021 - Systematic Review

Clinical application of polyurethane meniscal scaffold: A meta-analysis.

Li W, Pan J, Li J, Guo J, Zeng C, Xie D
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2021 - Clinical Study

Meniscal polyurethane scaffold plus cartilage repair in postmeniscectomy syndrome patients without malalignment improvesclinical outcomes at mid-term follow-up

Figueroa D, Figueroa F, Calvo R, Gomez C, Vaisman A.
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2021 - Systematic Review

Biosynthetic scaffolds for partial meniscal loss: A systematic review from animal models to clinical practice

Veronesi F, Di Matteo B, Vitale ND, Filardo G, Visani A, Kon E, Fini M
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2021 - Systematic Review

No differences in clinical outcome between CMI and Actifit meniscal scaffolds: a systematic review and meta-analysis

Reale D, Andriolo L, Previtali D, Grassi A, Candrian C, Zaffagnini S, Filardo G
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2021 - Clinical Study

Polyurethane scaffold implants for partial meniscus lesions: delayed intervention leads to an inferior outcome.

Condello V, Dei Giudici L, Perdisa F, Screpis DU, Guerriero M, Filardo G, Zorzi C.
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2021 - Review

Illustrative review of knee meniscal tear patterns, repair and replacement options, and imaging evaluation

Patel H, Skalski MR, Patel DB, White EA, Tomasian A, Gross JS, Vangsness CT, Matcuk GR Jr.
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2021 - Clinical Study

A comparison between Polyurethane and Collagen Meniscal Scaffold for Partial Meniscal Defects: Similar positive clinical results at a mean of 10-Years of Follow-up.

Reale D, Lucidi GA, Grassi A, Poggi A, Filardo G, Zaffagnini S
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2021 - Review

Biomaterials for meniscus and cartilage in knee surgery: state of the art.

Kluyskens L, Debieux P, Wong L+KL, Krych AJ, Saris DSF.
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2021 - Review

Meniscal Salvage: Where We Are Today

Anderson AB, Gaston J, LeClere LE, Dickens JF.
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2021 - Review

Meniscal repair: The current state and recent advances in augmentation

Bansal S, Floyd ER, A Kowalski M, Aikman E, Elrod P, Burkey K, Chahla J, LaPrade RF, Maher SA., Robinson JL, Patel JM.
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2020 - Clinical Study

Implantation of an Actifit® Polyurethane Meniscal Scaffold 18 Months After Subtotal Lateral Meniscectomy in a 13-Year-Old Male Adolescent.

Accadbled F, Pham TT, Thevenin Lemoine C, Sales de Gauzy J.
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2020 - Clinical Study

Polyurethane Meniscal Scaffold: Does Preoperative Remnant Meniscal Extrusion Have an Influence on Postoperative Extrusion and Knee Function?

Gelber PE, Torres-Claramunt R., Poggioli F, Pérez-Prieto D, Monllau JC.
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2020 - Clinical Study

Polyurethane Meniscal Scaffold for the Treatment of Partial Meniscal Deficiency: 5-Year Follow-up Outcomes: A European Multicentric Study.

Toanen C, Dhollander A, Bulgheroni P, Filardo G, Zaffagnini S, Spalding T., Monllau JC., Gelber P, Verdonk R, Beaufils P, Pujol N, Bulgheroni E, Asplin L, Verdonk P
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2020 - Clinical Study

Medial Meniscus Scaffold Implantation in Combination with Concentrated Bone Marrow Aspirate Injection: Minimum 3-Year Follow-up

Akkaya M, Şimşek ME, Gürsoy S, Çay N, Bozkurt M.
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2020 - Clinical Study

Muscle strength but not balance improves after arthroscopic biodegradable polyurethane meniscus scaffold application

F. Korkusuz, M., M. Akkaya, M. E. Simsek, N. Ozberk, S. Gursoy
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2020 - Clinical Study

Meniscal scaffold for the treatment of partial meniscal defect—clinical and radiological outcomes in a two-year follow-up

Bradbury N, Butt U, Hudetz D, Stenhouse G, Vuletic F
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2020 - Review

Meniscus Scaffolds for Partial Meniscus Defects

de Caro F, Dhollander A, Perdisa F, Verdonk P, Verdonk R
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2020 - Clinical Study

Functional and magnetic resonance imaging outcome after polyurethane meniscal scaffold implantation following partial meniscectomy

M Haspl, D Trsek, D Lovric, B Strahonja, D Matokovic
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2020 - Review

Meniscal substitution, a developing and long-awaited demand

Alexander P, Buerba R, Musahl V., Rothrauff BB, Shah N, Winkler PW, Zaffagnini S
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2020 - Clinical Study

Single-Stage Autologous Chondrocyte-Based Treatment for the Repair of Knee Cartilage Lesions: Two-Year Follow-up of a Prospective Single-Arm Multicenter Study

Slynarski K, Jong de WC, Snow M, Hendriks JAA, Wilson CE, Verdonk P
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2019 - Clinical Study

First Clinical Application of Polyurethane Meniscal Scaffolds with Mesenchymal Stem Cells and Assessment of Cartilage Quality with T2 Mapping at 12 Months.

Olivos-Meza A, Perez Jiminez FJ, Granados-Montiel J, Landa-Solis C, Cortes Gonzalez S, Jimenez Aroche CA, Valdez Chavez M, Renan Leon S, Gomez-Garcia R, Martinez-Lopez V, Ortega-Sanchez C, Parra-Cid C, Velasquillo Martinez C, Ibarra C.
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2019 - Systematic Review

Are the Biological and Biomechanical Properties of Meniscal Scaffolds Reflected in Clinical Practice? A Systematic Review of the Literature.

Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS.
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2019 - Basic Science

Novel multilayer meniscal scaffold provides biomechanical and histological results comparable to polyurethane scaffolds: An 8 week rabbit study.

Demirkiran ND, Havıtçıoglu H, Ziylan A, Cankurt Ü, Hüsemoglu B.
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2019 - Review

Meniscal allograft transplants and new scaffolding techniques.

Pereira H, Fatih Cengiz I, Gomes S, Espregueira-Mendes J, Ripoll PL, Monllau JC., Reis RL, Oliveira JM.
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2019 - Review

Treatment options for the symptomatic post-meniscectomy knee

Drobnič M, Ercin E, Gamelas J, Papacostas ET, Slynarski K, Zdanowicz U, Spalding T., Verdonk P
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2018 - Clinical Study

Magnetic Resonance Imaging and Functional Outcomes After a Polyurethane Meniscal Scaffold Implantation: Minimum 5-Year Follow-up.

Monllau JC., Poggioli F, Erquicia J, Ramirez E, Pelfort X, Gelber P, Torres-Claramunt R.
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2018 - Basic Science

Stiffness of meniscus tissue depends on tibio-femoral load and structural integrity of the meniscus root.

Starke C, Lohmann CH, Kopf S.
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2018 - Basic Science

Chondrocyte-based intraoperative processing strategies for the biological augmentation of a polyurethane meniscus replacement.

Vedicherla S, Romanazzo S, Kelly DJ, Buckley CT, Moran CJ
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2018 - Systematic Review

Similar clinical outcomes following collagen or polyurethane meniscal scaffold implantation: a systematic review.

Houck DA, Kraeutler MJ, Belk JW, McCarty EC, Bravman JT.
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2018 - Basic Science

Biomechanical performance of the Actifit scaffold is significantly improved by selection of irrigation fluid.

Hoburg A, von Roth P, Roy-Ali S, Ode JE, Wulsten D, Jung TM, Gwinner C.
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2018 - Review

Meniscus Repair and Replacement.

Cannon WD, DeHaven KE, Kurzweil PR
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2018 - Systematic Review

Polyurethane meniscal scaffolds lead to better clinical outcomes but worse articular cartilage status and greater absolute meniscal extrusion.

Shin YS, Lee HN, Sim HB, Kim HJ, Lee DH.
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2018 - Basic Science

Tissue Engineering of Large Full-Size Meniscus Defects by a Polyurethane Scaffold: Accelerated Regeneration by Mesenchymal Stromal Cells.

Koch M, Achatz FP, Lang S, Pfeifer CG, Pattappa G, Kujat R, Nerlich M, Angele P, Zellner J.
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2018 - Review

Orthopaedic regenerative tissue engineering en route to the holy grail: disequilibrium between the demand and the supply in the operating room.

Cengiz IF, Pereira H, de Girolamo L, Cucchiarini M, Espregueira-Mendes J, Reis RL, Oliveira JM.
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2017 - Clinical Study

Polyurethane-based cell-free scaffold for the treatment of painful partial meniscus loss.

Filardo G, Kon E, Perdisa F, Sessa A, Di Martino A, Busacca M, Zaffagnini S, Marcacci M.
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2017 - Clinical Study

Actifit polyurethane meniscal scaffold: MRI and functional outcomes after a minimum follow-up of 5-years.

Leroy A, Beaufils P, Faivre B, Steltzlen C, Boisrenoult P, Pujol N
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2017 - Systematic Review

Meniscal Transplants and Scaffolds: A Systematic Review of the Literature.

Dangelmajer S, Familiari F, Huri G., Kaymakoglu M, Simonetta R
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2017 - Review

An Overview of Scaffold Design and Fabrication Technology for Engineered Knee Meniscus.

Sun J, Vijayavenkataraman S, Liu H.
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2016 - Basic Science

In Vitro Testing of Scaffolds for Mesenchymal Stem Cell-Based Meniscus Tissue Engineering-Introducing a New Biocompatibility Scoring System.

Achatz FP, Kujat R, Pfeifer CG, Koch M, Nerlich M, Angele P, Zellner J.
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2016 - Review

MR-Imaging of Meniscal Substitution.

De Coninck T, Verdonk P, Verstraete K
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2016 - Basic Science

Influence of biomechanical and biochemical stimulation on the proliferation and differentiation of bone marrow stromal cells seeded on polyurethane scaffolds.

Teng S, Liu C, Guenther D, Omar M, Neunaber C, Krettek C, Jagodzinski M.
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2016 - Review

Meniscus tear surgery and meniscus replacement.

Forriol F., Vaquero J
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2016 - Review

The role of meniscal tissue in joint protection in early osteoarthritis.

Verdonk R, Madry H, Shabshin N, Dirisamer F, Peretti GM, Pujol N, Spalding T., Verdonk P, Seil R, Condello V, Di Matteo B, Zellner J., Angele P
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2016 - Clinical Study

Comparative Study of Collagen versus Synthetic-Based Meniscal Scaffolds in Treating Meniscal Deficiency in Young Active Population.

Bulgheroni E, Bulgheroni P, Campagnolo M, Gobbi A., Grassi A, Mudhigere A
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2016 - Clinical Study

Association of a hi-tech with a bio-tech technique in the treatment of early osteoarthritis of the knee: a case report.

Uboldi FM, Ferrua P, Parente A, Pasqualotto S, Berruto M.
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2016 - Clinical Study

Midterm follow-up after implantation of a polyurethane meniscal scaffold for segmental medial meniscus loss: maintenance of good clinical and MRI outcome.

Efe T, Figiel J, Gesslein M, Haberhauer F, Heyse TJ., Lorbach O, Roessler PP, Schuttler KF
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2016 - Clinical Study

Treatment of Painful, Irreparable Partial Meniscal Defects With a Polyurethane Scaffold: Midterm Clinical Outcomes and Survival Analysis.

Dhollander A, Verdonk P, Verdonk R
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2015 - Review

Clinical Application of Scaffolds for Partial Meniscus Replacement

Moran CJ, Withers DP, Kurzweil PR, Verdonk PC.
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2015 - Basic Science

What is the best way to fix a polyurethane meniscal scaffold? A biomechanical evaluation of different fixation modes.

Hardeman F, Corten K, Mylle M, Van Herck B, Verdonk R, Verdonk P, Bellemans J
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2015 - Review

Early assessment and prediction of potential impact of the implantation of polyurethane scaffold in partial meniscal lesions: a pilot horizon scanning activity in south Korea.

Tark JY, Jeong JY, Lee M, Park E, Park J, Park JJ, Lee S, Shin C.
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2015 - Systematic Review

Meniscal scaffolds: results and indications. A systematic literature review.

Andriolo L, de Caro F, Filardo G, Kon E, Marcacci M.
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2015 - Systematic Review

Meniscal Scaffolds – Preclinical Evidence to Support their Use: A Systematic Review.

Di Matteo B, Filardo G, Gostynska N, Kon E, Marcacci M., Perdisa F
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2015 - Clinical Study

Partial meniscus substitution with a polyurethane scaffold does not improve outcome after an open-wedge high tibial osteotomy.

Gelber PE, Isart A, Erquicia JI, Pelfort X, Tey-Pons M, Monllau JC.
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2015 - Clinical Study

Results of polyurethane implant for persistent knee pain after partial meniscectomy with a minimum of two years follow-up.

Martín-Hernández C, Ranera-García M, Díaz-Martínez JV, Muniesa-Herrero MP, Floría-Arnal LJ, Osca-Guadalajara M, García-Aguilera D.
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2015 - Clinical Study

Improvement in outcomes after implantation of a novel polyurethane meniscal scaffold for the treatment of medial meniscus deficiency.

Schuttler KF, Pöttgen S, Getgood A, Rominger MB, Fuchs-Winkelmann S, Roessler PP, Ziring E, Efe T
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2015 - Clinical Study

Actifit® scaffold implantation: Influence of preoperative meniscal extrusion on morphological and clinical outcomes.

Faivre B, Bouyarmane H, Lonjon G, Boisrenoult P, Pujol N, Beaufils P
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2015 - Clinical Study

The magnetic resonance aspect of a polyurethane meniscal scaffold is worse in advanced cartilage defects without deterioration of clinical outcomes after a minimum two-year follow-up.

Gelber PE, Petrica AM, Isart A, Mari-Molina R, Monllau JC.
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2014 - Basic Science

Cell distribution and regenerative activity following meniscus replacement.

Moran CJ, Atmaca S, Declercq HA, Cornelissen MJ, Verdonk PC.
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2014 - Clinical Study

Biodegradable polyurethane meniscal scaffold for isolated partial lesions or as combined procedure for knees with multiple comorbidities: clinical results at 2 years.

Kon E, Filardo G, Zaffagnini S, Busacca M, Di Martino A, Di Matteo B, Marcheggiani Muccioli GM, Marcacci M.
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2014 - Clinical Study

Polyurethane scaffold in lateral meniscus segmental defects: clinical outcomes at 24 months follow-up.

Bouyarmane H, Beaufils P, Pujol N, Bellemans J, Roberts S, Spalding T., Zaffagnini S, Marcacci M., Verdonk P, Womack M, Verdonk R
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2014 - Clinical Study

Actifit synthetic meniscal substitute: experience with 18 patients in Brest, France.

Baynat C, Andro C, Vincent JP, Schiele P, Buisson P, Dubrana F, Gunepin FX.
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2014 - Review

Restoration of the meniscus: form and function.

Hutchinson ID, Moran CJ, Potter HG, Warren RF, Rodeo SA
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2014 - Review

Updates in biological therapies for knee injuries: menisci.

Arliani GG, Cohen M., da Costa Astur D, Debieux P, Kaleka CC
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2014 - Review

Meniscal scaffolds.

Goodwillie AD., Myers KR, Sgaglione NA
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2013 - Systematic Review

Scaffolds for partial meniscal replacement: an updated systematic review.

Papalia R, Franceschi F, Diaz Balzani L, D'Adamio S, Maffulli N, Denaro V.
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2013 - Clinical Study

Two-year follow-up study on clinical and radiological outcomes of polyurethane meniscal scaffolds.

De Coninck T, Huysse W, Verdonk P, Verdonk R, Verstraete K, Willemot L
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2013 - Clinical Study

Polyurethane scaffold for the treatment of partial meniscal tears. Clinical results with a minimum two-year follow-up.

Bulgheroni P, Bulgheroni E, Regazzola G, Mazzola C.
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2013 - Basic Science

Biomechanical comparison of menisci from different species and artificial constructs.

Sandmann GH, Adamczyk C, Garcia EG, Doebele S, Buettner A, Milz S, Imhoff AB, Vogt S, Burgkart R, Tischer T.
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2012 - Clinical Study

The safety and short-term efficacy of a novel polyurethane meniscal scaffold for the treatment of segmental medial meniscus deficiency.

Efe T, Getgood A, Schofer MD, Fuchs-Winkelmann S, Mann D, Paletta JR, Heyse TJ.
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2012 - Clinical Study

Meniscal scaffolds: early experience and review of the literature.

Carmont MR, Dhillon MS, Saithna A, Spalding T., Spencer SJ, Thompson P
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2012 - Review

Partial meniscus substitution with tissue-engineered scaffold: an overview.

Mouzopoulos G, Siebold R
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2012 - Review

Synthetic meniscus replacement: a review.

Vrancken AC, Buma P, van Tienen TG
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2012 - Basic Science

Influence of perfusion and compression on the proliferation and differentiation of bone mesenchymal stromal cells seeded on polyurethane scaffolds.

Liu C, Abedian R, Meister R, Haasper C, Hurschler C, Krettek C, von Lewinski G, Jagodzinski M.
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2012 - Basic Science

Effect of load on the repair of osteochondral defects using a porous polymer scaffold.

Hannink G, de Mulder EL, van Tienen TG, Buma P
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2012 - Clinical Study

Successful treatment of painful irreparable partial meniscal defects with a polyurethane scaffold: two-year safety and clinical outcomes.

Verdonk P, Beaufils P, Bellemans J, Djian P, Heinrichs EL., Huysse W, Laprell H, Siebold R, Verdonk R, Actifit Study Group
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2011 - Systematic Review

Tissue engineering and regenerative medicine strategies in meniscus lesions.

Pereira H, Frias AM, Oliveira JM., Espregueira-Mendes J, Reis RL
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2011 - Basic Science

A pre-clinical test platform for the functional evaluation of scaffolds for musculoskeletal defects: the meniscus.

Bonassar LJ, Maher SA., Potter HG, Rodeo SA, Warren RF, Wright TM
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2011 - Basic Science

Changes in articular cartilage after meniscectomy and meniscus replacement using a biodegradable porous polymer implant.

Hannink G, van Tienen TG, Schouten AJ, Buma P
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2011 - Basic Science

Frictional properties of the meniscus improve after scaffold-augmented repair of partial meniscectomy: a pilot study.

Galley NK, Gleghorn JP, Rodeo S, Warren RF, Maher SA., Bonassar LJ
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2011 - Clinical Study

Tissue ingrowth after implantation of a novel, biodegradable polyurethane scaffold for treatment of partial meniscal lesions.

Verdonk R, Verdonk P, Huysse W, Forsyth R, Heinrichs EL.
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2010 - Basic Science

Implantation of a synthetic meniscal scaffold improves joint contact mechanics in a partial meniscectomy cadaver model.

Brophy RH, Cottrell J, Rodeo SA, Wright TM, Warren RF, Maher SA.
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2010 - Basic Science

Evaluation of a porous polyurethane scaffold in a partial meniscal defect ovine model.

Maher SA., Rodeo SA, Doty SB, Brophy R, Potter H, Foo LF, Rosenblatt L, Deng XH, Turner AS, Wright TM, Warren RF
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2008 - Basic Science

Effect on tissue differentiation and articular cartilage degradation of a polymer meniscus implant: A 2-year follow-up study in dogs.

Welsing RT, van Tienen TG, Ramrattan N, Heijkants R, Schouten AJ, Veth RP, Buma P
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2006 - Basic Science

Meniscal replacement in dogs. Tissue regeneration in two different materials with similar properties.

Tienen TG, Heijkants RG, de Groot JH, Schouten AJ, Pennings AJ., Veth RP, Buma P
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2005 - Basic Science

Assessment of tissue ingrowth rates in polyurethane scaffolds for tissue engineering.

Ramrattan NN, Heijkants RG, van Tienen TG, Schouten AJ, Veth RP, Buma P
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2005 - Review

Polyurethane scaffolds for meniscal tissue regeneration.

de Groot JH
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2004 - Basic Science

Design, synthesis and properties of a degradable polyurethane scaffold for meniscus regeneration.

Heijkants RG, van Calck RV, de Groot JH, Pennings AJ., Schouten AJ, van Tienen TG, Ramrattan N, Buma P, Veth RP
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2004 - Review

Tissue engineering of the meniscus.

Buma P, Meel van M, van Tienen TG, Veth RP
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2003 - Basic Science

A porous polymer scaffold for meniscal lesion repair–a study in dogs.

Tienen TG, Heijkants RG, Buma P, de Groot JH, Pennings AJ., Veth RP
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2002 - Basic Science

Tissue ingrowth and degradation of two biodegradable porous polymers with different porosities and pore sizes.

Buma P, de Groot JH, Heijkants RG, Pennings AJ., van Tienen TG, Veth RP
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2000 - Basic Science

Solvent-free fabrication of micro-porous polyurethane amide and polyurethane-urea scaffolds for repair and replacement of the knee-joint meniscus.

Spaans CJ, Belgraver VW, Rienstra O, de Groot JH, Veth RP, Pennings AJ.
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1996 - Basic Science

Use of porous polyurethanes for meniscal reconstruction and meniscal prostheses.

de Groot JH, de Vrijer R, Pennings AJ., Klompmaker J, Veth RP, Jansen HW
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1996 - Basic Science

Meniscal replacement using a porous polymer prosthesis: a preliminary study in the dog.

Klompmaker J, Veth RP, Jansen HW, Nielsen HK, de Groot JH, Pennings AJ.
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1991 - Basic Science

Porous polymer implant for repair of meniscal lesions: a preliminary study in dogs.

Klompmaker J, Jansen HW, Veth RP, de Groot JH, Nijenhuis AJ, Pennings AJ.
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